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Tirzepatide is not recommended for individuals with a personal or family history of medullary thyroid carcinoma or those diagnosed with multiple endocrine neoplasia syndrome type 2, due to a theoretical risk of thyroid tumors based on animal studies

Once-weekly glucagon-like peptide-1 receptor agonist dulaglutide significantly decreases glycated haemoglobin compared with once-daily liraglutide in J apanese patients with type 2 diabetes: 52 weeks of treatment in a randomized phase III study

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Obesity pathophysiology is multifactorial and involves social, psychological, and behavioral factors, genetic and metabolic predisposition