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The constipation scale comprises 8 items: frequency of defecation, difficulty, completeness, pain assessment, duration of defecation (in minutes), assisted defecation, number of unsuccessful defecations attempts per 24 h, and duration of constipation (in years)

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Additionally, abolishment of myocardial protection by the PI3 K inhibitor LY294002 and by the p44/42 mitogen-activated protein kinase inhibitor UO126 implicates that both of this prosurvival pathways take part in cardioprotection mediated by GLP-1

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[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Health disparities: gaps in access, quality and affordability of medical care

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