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His home medications include tirzepatide 2.5 mg subcutaneous injection once weekly, glipizide 5 mg daily, losartan 100 mg daily, and tadalafil once daily
one patient had an initial improvement in both glycemia and weight followed by weight regain and deterioration of glycaemic control, and one patient experienced only glycemia improvement with weight gain (42)

The Canadian Adult Obesity Clinical Practice Guidelines released in 2020 indicated that obesity increases the risk of developing cardiovascular disease and certain types of cancers, which are some of the leading causes of early death in these patients

According to several meta -analyses and reviews, psychotherapies, specifically cognitive behavior therapy-based approaches, are widely considered the most effective intervention for BED [9]

doi: 10.1111/jch.12660
Conditions like cauda equina syndrome demand emergency decompression surgery to preserve bowel or bladder control and lower extremity function
