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As healthcare systems grapple with the burdens of these conditions, the availability of effective pharmacotherapy can alleviate some of the strain on medical resources

GLP-1 medications can lead to up to 3040% of weight lost coming from lean muscle mass, whereas ESG tends to result in only about 1015% muscle loss, making it more effective at preserving lean body mass during weight reduction due to its mechanical rather than hormonal weight loss mechanism

semaglutide, tirzepatide), regain is even fasterup to 0.8 kg/month, with return to baseline in ~1.5 years

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Compounded drugs can be important for overcoming shortages or meeting unique patient needsbut compounders should not try to compound drugs in a way that circumvents FDAs approval process. The FDA claims the companies are mass marketing their GLP-1s as similar alternatives to FDA-approved drugs

However, these variations often lack robust clinical data to confirm their effectiveness and safety