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Although much attention has been given to the role of the brain in energy homeostasis, at present, remodelling of the gut through bariatric surgery is the only effective treatment for severe obesity

For instance, rapid weight loss and reduced A1C could cause other side effects

This question reflects growing interest in GLP-1 receptor agonists like semaglutide (Wegovy) and tirzepatide (Zepbound) for chronic weight management

I generally tell people that if theyre having mild nausea or constipation, see if youre able to ride it out, he says

But they also lead to weight loss, and many doctors also prescribe them off-label to patients with obesity

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