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[DOI] [PubMed] [Google Scholar] Perley MJ, Kipnis DM

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Total weight loss by week 12 typically ranges from 5% to 8% of starting body weight, depending on the medication and dose

Some people may also experience an upset stomach, diarrhea, or nausea
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Intestinal FXR mediates the hepatic T3 action on GLP-1 and glucose homeostasis To test whether intestinal FXR signaling was essential for the T3 action observed in this study, intestine-specific FXR-null mice (IFXRKO) were employed 31