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Many users report that nausea on tirzepatide is most intense during the first few weeks of starting or after a dosage increase

Compared with the year before GLP-1 RA treatment, it was associated with a 26% lower asthma exacerbation rate overall, and a 14% drop in the use of inhaler relievers

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It produced a record-setting 24.2% average weight loss over 48 weeks in Phase 2 trials

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They helped identify GLP-1 and GLP-2, and demonstrated how boosting GLP-1 levels could improve insulin response