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Retatrutide (LY3437943) is a research-grade lyophilised peptide supplied as a sterile white powder

John Horneff, an associate professor of orthopedic surgery at the University of Pennsylvania and the lead author of the study, said the potential side effects of GLP-1 drugs came to light when some patients developed serious tendon tears after relatively minor injuries

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Equivalence in gastric emptying (acetaminophen AUC 0300 min ) at the end of the 5-week treatment periods was observed for liraglutide 1.8 mg versus 3.0 mg, and liraglutide versus placebo, as 90% CIs for the estimated ratios were fully contained within the interval (0.801.25) (Table 1)