summit clinical trial tirzepatide In pts wiht HFpEF and obesity, (Mounjaro®) significantly reduces HF hospitalization, diuretic intensification, or CV death by 38% vs placebo in https://t.co/8ZHm4gySiL Has Tirzepatide Scaled the HFpEF/Obesity

However, some studies suggest tirzepatide may produce greater average weight loss because it targets two hormones involved in appetite regulation instead of one.

PLMD can include uncontrolled movement of both legs and arms, although it predominantly affects the lower extremities

There is even speculation of whether longevity could be impacted, since obesity and diabetes reduction improve life expectancy some analysts have asked if GLP-1 drugs might earn their discoverers a Nobel Prize given the broad impact ( [152] )

Currently, an estimated 40% of adults in the United States are living with obesity, a chronic health condition that can increase the likelihood of type 2 diabetes, high blood pressure, heart disease, stroke and even certain cancers

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An interim readout of the phase 2 trial showed that the drug led to lower amounts of serum lipids including total cholesterol and low-density lipoprotein (LDL-C), improved blood pressure and contributed to weight loss