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When combined (as in the investigational drug CagriSema ), they show promising synergistic effects for greater weight loss than either drug alone

Doses listed as Available on the FDAs shortage list are backordered at pharmacies across the country Obesity rates are expected to exceed 50% in the majority of states by 2030 Patients with obesity have, on average, ~$2000 higher healthcare costs per year Obesity is associated with 8 out the 10 leading causes of death and 200 health complications There is a nationwide shortage of healthcare providers, with the problem only expected to worsen (50% are older than 55 years old) There is intense stigma associated with obesity and treatment for the condition in the media, healthcare, socially and professionally Access is unequal

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This increased risk is commonly seen among patients with diabetes and is in connection with worsened clinical conditions and higher mortality in patients with acute ischemic stroke (AIS)

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