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This includes dietary inputs, microbial balance, and targeted interventions that support long-term signaling stability

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2,3 CKD is a common complication of type 2 diabetes, with approximately 40% of people with type 2 diabetes also experiencing CKD

6 Aberrant glucagon responses promoting hyperglycemia may be due to the impaired regulation of glucagon and insulin secretion, as well as disrupted alpha cell responses to insulin

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