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If these drugs become more accessible, they could significantly reduce complications like myocardial infarctions, strokes, end-stage kidney disease, and need for invasive weight loss surgeries

Bowsman et al

Ma C, Avenell A, Bolland M, Hudson J, Stewart F, Robertson C, et al

Glucagon Suppression: They suppress the release of glucagon, a hormone that raises blood sugar levels

However, if the A1c is 60 mg/mmol, or progressive increase in UACR despite appropriate therapy, eGFR 30% increase in serum creatinine within 3 months of starting SGLT2i, ACEi, or ARB, inability to achieve target BP, or signs/symptoms of another underlying kidney disease, such as glomerulonephritis

UVA Healths Varney, who has consulted for Eli Lilly, said not to give up on trying to get GLP-1s covered