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Although it seems counterintuitive that cardioinhibitory drugs such as beta-blockers would be used in cases of systolic dysfunction, clinical studies have shown conclusively that some specific beta-blockers improve cardiac function and reduce mortality

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(2025) National Library of Medicine [Accessed 21 April 2026] Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity

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[7] In practice, some protocols use 1 mg IM monthly for maintenance once levels are stabilized