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Tirzepatide is a biased agonist favouring cAMP production over -arrestin recruitment, which may reduce receptor internalisation and potentially enhance GLP-1 signalling [70] GLP-1 and control of gastric emptying: normal physiology and diabetes GLP-1 inhibits gastrointestinal motility and gastric secretion (Fig

Qvigstad E, Gulseth HL, Risstad H, le Roux CW, Berg TJ, Mala T, Kristinsson JA

Those with significant medical co-morbidities, prior CSF diversion procedures, neurovascular stenting or optic nerve sheath fenestration, those currently using GLP-1 receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors or taking drugs that could reduce ICP were excluded

Conclusions Overall, it is concluded that there are no notable reasons why diabetics with reasonably healthy eyes cannot wear contact lenses

Seek emergency care for signs of severe allergic reaction, such as trouble breathing or facial swelling

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