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Description
Your GP or endocrinologist can assess whether you fulfil NICE criteria, which typically require a BMI 35 kg/m with weight-related comorbidities, or 30 kg/m with type 2 diabetes for weight management indications

doi: 10.1016/j.brainres.2010.05.002

(Right) GLP-1 receptor agonist (GLP-1RA) reduces cholesterol accumulation by affecting the expression of genes in the hepato-enteral circulation and cholesterol reverse transport pathway, such as farnesoid X receptor (FXR), fibroblast growth factor-15 (FGF15), fibroblast growth factor receptor 4 (FGFR4), cytochrome P450 family 7 subfamily A member 1 (Cyp7a1), proprotein convertase subtilisin/kexin type 9 (PCSK9), low-density lipoprotein receptor (LDLR), etc

Ball AK, Howman A, Wheatley K, et al
In May 2022, Mounjaro was approved by the FDA for treating type 2 diabetes

The pharmacology and clinical pharmacology of indapamide
