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PMID: 39003287

While prescription GLP-1 medications can be effective, they are not without risks

Triple-agonist compounds such as RETA are studied to explore whether simultaneous pathway engagement produces distinct signalling patterns compared to more limited receptor activation

They discuss a case of a 52-year-old woman with limited cutaneous systemic sclerosis who presents with progressive symptoms of heart failure and is found to have a severe, non-ischemic cardiomyopathy

Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as an Add-On to Metformin, Thiazolidinediones, or Their Combination in Patients With Type 2 Diabetes (SUSTAIN 2): A 56-Week, Double-Blind, Phase 3a, Randomised Trial

Oral Wegovy is also being studied for its potential to reduce the risk of serious cardiac health events, according to the report