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Vasoactive intestinal polypeptide mediates cholecystokinin-induced relaxation of the sphincter of Oddi

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When researchers tested pure GLP-1 receptor agonists, including semaglutide , liraglutide, and exenatide, none of them increased the beating rate of isolated heart tissue

Health Policy, Seigerman wrote

Therefore, the efficacy and specific benefits of GLP-1RAs in HFpEF require further investigation