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But how does semaglutide stack up against the first-ever weight loss medication, phentermine

In patients with obesity (mean age 51.3 years, 65.6% women), semaglutide compared with non-GLP-1RA anti-obesity medications was associated with lower risk for incident CUD in patients with no prior history CUD (HR: 0.56, 95% CI: 0.420.75), and recurrent CUD diagnosis in patients with a prior history CUD (HR: 0.62, 95% CI: 0.460.84)

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Gary Clayman, MD, explained that while animal studies have suggested a link between GLP-1 therapies and C-cell issues leading to medullary thyroid cancer, these findings have not been replicated in human studies

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