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Hyponatremia (low sodium) can cause confusion, headache, seizures, and in severe cases, cerebral edema

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Pradhan R., Lu S., Yin H., Yu O.H.Y., Ernst P., Suissa S., Azoulay L

Cases of remitting seronegative symmetrical synovitis with pitting edema syndrome, presenting as symmetrical synovitis with dorsal hand and foot edema, have also been reported in individuals receiving DPP-4 inhibitors [13, 34]

Villars, E

Research shows patients typically regain 50-80% of lost weight within 6-12 months after discontinuing treatment