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As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)

Aging is a diverse and multifaceted process as different organs within an individual undergo distinct aging trajectories influenced by genetic, environmental, and lifestyle factors [78]

Through systematic evaluation based on report frequency and reporting odds ratio (ROR) calculations, the top 50 preferred terms (PTs) were identified for comprehensive visualization (Supplementary Fig

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