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When you inject semaglutide, it activates GLP-1 receptors in the brain that regulate hunger signals

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Frequent monitoring of the INR is required until a patient is stabilized on a dose within the therapeutic INR range

We've got the thermic effect, and now we have satiety

This includes an initial water weight drop in weeks 1 to 3, a common plateau at week 4, and steadier fat loss starting week 5 when the dose increases from 0.25mg to 0.5mg