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If retatrutide and other GLP-1 medications also reduce LDL, it makes them powerful dual-action therapies: not just fighting obesity and diabetes, but also reducing heart disease risk

Studies are currently underway to better understand this potential side effect

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Most common side effects are stomach-related: Nausea (the most frequent complaint) Diarrhea Vomiting Constipation These symptoms usually happen in the first few weeks of treatment and improve over time

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In contrast, asymptomatic patients without risk factors generally do not require pre-treatment screening