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This suggests the possibility that some native polyphenols, while being active, may be of greater benefit to the body after undergoing some degree of microbiome-mediated metabolism

A potential clinical advantage of employing low dose semaglutide in HFpEF is the possibility of preserving skeletal muscle mass while retaining cardioprotective benefits
Pending positive outcomes from ongoing and forthcoming RCTs, GLP-1 RA medications may become a pharmacotherapeutic approach for treating polysubstance use. Alcohol Addiction Among all substances, alcohol is by far the most investigated when it comes to GLP-1 RAs

The group includes pure GLP-1 drugs (semaglutide) and dual GIP/GLP-1 drugs (tirzepatide)
p = 0.005) than with the placebo (1.62%

Mol Metab 2017;6:13391349
