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That is a significant amount of time without full benefit, and it undermines the very purpose of the alternating strategy

Clonal HEK293 cells stably expressing either untagged human GIPR or human GLP-1R at various levels of receptor density were used for measurement of cAMP accumulation using the Gs Dynamic Assay and homogenous time-resolved fluorescence (62AM4PEJ, PerkinElmer)

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