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Methods Network characteristics We performed a retrospective cohort study of all patients aged 18 or over with type 1 diabetes using the TriNetX platform

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McFall-Ngai M, Hadfield MG, Bosch TCG, Carey HV, Domazet-Loo T, Douglas AE, Dubilier N, Eberl G, Fukami T, Gilbert SF, Hentschel U, King N, Kjelleberg S, Knoll AH, Kremer N, Mazmanian SK, Metcalf JL, Nealson K, Pierce NE, Rawls JF, Reid A, Rumpho M, Sanders JG, Tautz D, Wernegreen JJ

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This effect is attributed, in part, to the glucagon receptor agonism, which is believed to directly enhance hepatic fat oxidation

This trade-off makes sense for patients who prioritize tolerability over speed of results