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The key with insoluble fiber on GLP-1 medications is moderation and hydration

Renal protection by sodium-glucose cotransporter 2 inhibitors and its underlying mechanisms in diabetic kidney disease

Rooks & Garrett (2016, Nat Rev Immunol ) describe SCFAs as central immune-metabolic regulators

A PubMed Central-hosted review of peptide-based obesity treatments describes "nausea, vomiting and loss of appetite" as common effects of the GLP-1 drug class (pmc.ncbi.nlm.nih.gov)

a far cry from hibernating at home and feeling self-conscious about his gut

The focus should always be on medical supervision and healthy lifestyle habits
