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Description
In people with obesity and established cardiovascular disease but without diabetes, semaglutide 2.4 mg resulted in 20% reduction in major adverse cardiovascular events [(MACE), death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke] compared to placebo (SELECT trial) after a mean follow-up of 39.8 months this is the first trial demonstrating cardiovascular benefit for an obesity pharmacotherapy [110]
Your doctor can assess your individual risk factors

14(4): e36727
doi: 10.1172/JCI78371

"It does take quite a bit," Dr Emil said of the weight loss achievements seen advertised on these medications

So when they were launched on the market, they rapidly went into short supply they couldn't keep up with the number of prescriptions
