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In mouse models of Alzheimers disease, triple agonists play a neuroprotective role and ameliorate cognitive deficits by significantly reducing hippocampal amyloid-, phosphorylated tau aggregates, and neuroinflammation, and stimulating neurogenesis and brain-derived neurotrophic factor expression (Li et al., 2018

Frontiers in Pharmacology, 11, 1270

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Over the years, researchers have followed this drug to see who it harms in certain organ systems and haven't seen any significant red flags in the heart or blood vessels [7]
