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This is why your provider starts you on a lower dose and gradually increases it

Sulphurous burpsoften described as having a 'rotten egg' smellresult from hydrogen sulphide gas production in the digestive system, whilst diarrhoea affects more than 10% of patients according to clinical trial data

Rybelsus (Semaglutide) - Lowest Price Quick Overview Rybelsus (semaglutide) improves blood sugar control in adults with type 2 diabetes

And stopping is far more common than the marketing suggests: one large 2025 analysis found that most people who start a GLP-1 for weight loss stop within two years

RELATED: Trump says GLP-1 weight-loss drugs coming at $50 for Medicare patients The Trump administration had said that coverage of the drugs for obesity will expand to Medicare patients starting next year, but Trump announced May 2 that Zepbound and Wegovy would be available to Medicare patients for $50 a month starting July 1