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A pathology professor at Standard explained the risks of this practice, which include accidental overdose, vomiting, severe dehydration, and sepsis from contaminated ingredients or preparing injections in unsterile conditions

This point has also been raised for beneficial effects of GLP1 receptor agonists in Parkinson's disease, due to a lack of expression of GLP1 receptors by dopaminergic substantia nigra neurons (Knudsen, 2019)

Patients do not know they have diabetic gastroparesis until they are put on a glucagon-like peptide 1 (GLP-1) receptor agonist such as semaglutide to manage their blood glucose

10.1016/j.bbadis.2025.167758

Bonarrigo says