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Additionally, oral semaglutide for weight loss in non-diabetics is a viable option, offering flexibility to those not diagnosed with diabetes but who require weight management assistance

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These medications are incredibly popular and are helping to get people to drop body fat and live healthier lives

Asthma symptoms were also reduced [7]

Novo Nordisks own indirect treatment comparison (the ORION study, presented at Obesity Medicine Association 2026) suggested greater weight loss with oral semaglutide than with orforglipron, though that analysis was industry-funded and drew skepticism from independent researchers