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Bispecific or tandem CARs frequently function through an OR-gate mechanism, in which recognition of either antigen is sufficient to activate T cells, thereby preserving cytotoxicity even when one antigen becomes partially or completely downregulated under therapeutic pressure

Not sure why many on these threads cant comprehend this

For an athlete whose performance depends on power, explosiveness, and strength, thats a real cost that may offset the body composition benefit entirely. This occurs, he said, because people on GLP-1s dont selectively burn fat

Women, for example, may need higher levels of iron and folate, since both nutrients support red blood cell production and reproductive health

Del Prato, S., Kahn, S

Hypoglycemia Risk The glucose-dependent nature of GLP-1 and GIP activity provides inherent protection against hypoglycemia