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Diala Alatassi is a highly accomplished physician specializing in internal medicine and obesity medicine

Randomisation of patients was done to once-daily semaglutide, liraglutide, or placebo as 2:2:1 in one of four volume-matched doses (Both semaglutide 0.05, 0.1, 0.2, or 0.3 mg and liraglutide 0.3, 0.6, 1.2, or 1.8 mg, within each volume-matched dose group were compared)

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Most of the studies were conducted in the USA except one in the Netherlands [28]

On the cardiovascular side, the SUSTAIN-6 trial in 2016 was one of the first to report a significant reduction in major adverse cardiovascular events with semaglutide in adults with type 2 diabetes and high cardiovascular risk (Marso et al., NEJM, 2016)