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Unfortunately, most regain two-thirds of their lost weight within a year as well as worsening of metabolic health indicators (Mozaffarian et al., 2025
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AT-7687, a novel GIPR peptide antagonist, combined with a GLP-1 agonist, leads to enhanced weight loss and metabolic improvements in cynomolgus monkeys
( 10.1210/endrev/bnaa032) [DOI] [PMC free article] [PubMed] [Google Scholar] McLean BA Wong CK Kaur KD Seeley RJ & Drucker DJ
