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Compr Rev Food Sci Food Saf

A phase 3, multi-center trial called the Exenatide PD3 Study is coming to an end in the United Kingdom, with initial results expected in summer 2024

In the RWD, data are only available through normal clinical care when patients have interactions with the healthcare system

doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies

This limits our ability to determine whether diabetes itself constitutes an independent risk factor for adverse gastrointestinal outcomes with these agents

For almost everyone, the answer to that question is now no