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[12] [13] Red flags that require urgent medical attention include unexplained weight loss, fever, focal neurological deficits, or inflammatory joint swelling, as these may indicate alternative diagnoses requiring different management

For context, licensed GLP-1 receptor agonists used in weight management such as semaglutide 2.4 mg (Wegovy) cost in the region of 200300 per month when prescribed privately in the UK (indicative figures as of mid-2025

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Now add a GLP-1 to that landscape, and the conversation around GLP-1s and perimenopause becomes much more important

However, GLP-1s have also been reported to improve fertility in some cases, particularly in patients with PCOS, due to their ability to enhance insulin sensitivity and reduce systemic inflammation

Pairing with nutrient-dense foods ensures you get maximum nutritional value from smaller meals