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The clinical nuance is what Pfizer doesnt try to oversell: a non-placebo-adjusted number is not the same as a placebo-adjusted treatment effect

That delayed digestion can let bacteria work longer on food, increasing fermentation and hydrogen sulfide output for some people

The key is patients need to be informed of what the medical evidence tells us, have to put it into context, with a goal to assist them in making an informed decision

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This leads to the formation of closely eluting impurities such as oligomers, D-Asp9 and related derivatives, which are notoriously difficult to remove during purification and pose critical quality concerns for pharmaceutical-grade material