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At the time of the 2025 Super Bowl, there was a shortage of the branded GLP-1 drugs semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound, which opened the door for compounding pharmacies to sell non-identical versions under specific FDA regulations

PMID: 39290798

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A new prescription and a new prior authorization are required when you switch from one covered GLP-1 medication to another

The mechanisms include weight loss reducing upper airway fat deposition, improved respiratory muscle tone with reduced adiposity, and possible direct effects on central respiratory control through GLP-1R in the brainstem

State boards of pharmacy primarily oversee these facilities. Some compounded semaglutide products may contain extra ingredients that arent found in the commercial products, such as vitamins B12 and B6