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Mechanisms to elevate endogenous GLP-1 beyond injectable GLP-1 analogs and metabolic surgery

I no longer feel self-conscious about my neck, and Ive regained my perfect jawline.- Emily Johnson, 42 years old, Los Angeles, California, USA Why have you been unable to lose weight

This newly charted pathway - separate from previously described mechanisms that broadly affect appetite - could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder

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These five, across sectors, show how quickly a trusted category can become obsolete when the delivery mechanism changes