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Recent evidence from the STEP-HFpEF and STEP-HFpEF-DM trials provides the first robust data supporting the efficacy of GLP-1 RAs, specifically semaglutide, in improving the quality of life in obese patients with HFpEF

If prescribed to treat Type 2 diabetes: If a GLP-1 is prescribed by a healthcare provider to treat type-2 diabetes, the HSA can be used to pay the expense on a tax-free basis

Berberine alleviates Alzheimers disease by regulating the gut microenvironment, restoring the gut barrier and brain-gut axis balance

So before we move quickly to external GLP-1 support, a more important question is: Are we activating endogenous pathways effectively

Much has been learned about GLP-1s over many years, but little is understood about why the degree of response to them varies so widely, Daniel J

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