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GLP-1 receptor agonists reduce appetite and slow gastric emptying, creating a caloric deficit that leads to fat mobilisation throughout the body

For patients first prescribed an AOM in September 2025, 47.5% filled a GLP-1 RA within 60 days

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In fact, between 1960 and 2010 the proportion of the US people considered to be obese doubled from 15 to 30% (Ravandi et al., 2025)

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CGM: continuous glucose monitoring