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Topical pain relievers, heat/cold therapy, physical activity, and stretching offer non-drug alternatives

Studies in PCOS women note increased ovulation and induction of pregnancies after weight loss with these agents

A banana or energy bar 60 minutes before helps
The mechanism of how GIPR and GLP-1R agonism synergizes to enhance body weight loss are not known, but a series of experimental results indicates that GIP acts on the GIP receptor in the brain to decrease body weight via inhibition of food intake (156, 179, 187)
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Cardiovascular side effects Another area of concern with retatrutide is its potential impact on the cardiovascular system
