glp-1 drugs insurance coverage of Obesity Therapies in State-Regulated Markets NCSL | Policymakers and health

doi:10.1016/j.ntt.2021.106984 Price SAL, Nankervis A

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The most common risks of oral GLP-1s like Rybelsus, Wegovy pill, and Foundayo include : Acute pancreatitis Diabetic retinopathy complications (diabetes-related vision changes) Hypoglycemia (low blood sugar), especially when used with insulin Kidney or gallbladder issues Severe gastrointestinal reactions Allergic reactions Pulmonary aspiration during general anesthesia or deep sedation All three GLP-1s also carry a black box warning for thyroid tumors based on animal studies

Figure 26: Photograph of Professor Jens Holst with Dr Karen Thorne, a member of his laboratory, carrying out an experiment with a perfused pig pancreas in the 1990s, credit: Holst

Biochem Biophys Res Commun

Individuals using GLP-1 treatments, such as those in programs like Tyde Wellness, report an average body weight reduction of 15% after 68 weeks, with many achieving weight loss of over 20-25% within a year