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In this study ovariectomized (surgically menopausal) female mice were used

Pens are designed for maintenance dosing at 1 mg and 2 mg per injection once the maintenance dose is reached

Furthermore, although Wheeler et al

Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats

Some people may also experience GI side effects
