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It is the first in vivo study to systematically evaluate the effects of repeated SNAC exposure on gut microbiota composition, function, and metabolic outcomes

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Sci Rep 12 , 1567 (2022)

Endogenous GLP-1 acts in a paracrine fashion to stimulate adjacent GLP-1R on the dendritic terminals of the celiac and gastric branches of VANs that innervate the gut, reducing food intake via vagal-NTS glutamatergic signaling and also mediate insulin release via vago-vagal reflex [190]

GLP-1 Microdose