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SURMOUNT-1 (NEJM, 2022) the Tirzepatide Phase 3 trial enrolled 2,539 participants

Is it safe with diabetes or high blood pressure
Instead, they are made in pharmacies when there is a medical reason, sometimes to help with possible B12 deficiencies that might happen during use

individuals with higher initial weights tend to experience greater absolute weight loss

Agents that provide benefits beyond glucose lowering - such as reducing heart disease risk - are rewarded with broader guideline adoption and wider clinical utilization

This means we dont know very much about how retatrutide interacts with alcohol yet
