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These metabolic abnormalities contribute to the increased inflammation that plays a key role in the pathogenesis of the disease [5]

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Semaglutide ( n = 4, SUSTAIN-6 [14], PIONEER-6 [15], SELECT [8], SOUL [16])

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Built on top of maximised RAAS (renin-angiotensin-aldosterone system) blockade, SGLT2i remain part of the foundation, recommended broadly for adults with CKD and albuminuria or heart failure, including many without T2D

However, these findings make GLP-1RAs a valuable therapeutic option for the management of WR in post-bariatric surgery patients, offering additional benefits apart from WL