tirzepatide versus semaglutide Comparison of for mean change in HbA1c Tirzepatide vs Semaglutide: What's the
Description
However, the use of GLP1RAs did not exert clinically significant changes in the AUC or differences in clinically relevant endpoints

Diabetes - GLP-1 agonists should be primarily considered in patients with type 2 diabetes with suboptimal glycaemic control despite maximal tolerated dose of metformin (+/- other agents) especially where weight loss is desired and/or significant stroke risk is present

GLP-1 receptor agonists, such as semaglutide and liraglutide, are primarily used to manage type 2 diabetes and have been shown to aid in weight loss

The researchers found that turning off GLP-1 in the brain didnt affect the normal daily intake of food, but instead was important in several specific situations: prolonged fasting, large feedings, and stress-induced appetite loss.[ref] Controlling binging, regulating satiety: Essentially, the neurons activated by GLP-1 help to limit binging after a fast they keep you from massively overeating after not eating for a while
Common Side Effects and How Timing Can Help Nausea, vomiting, and diarrhoea affect up to 40% of patients and typically improve within 48 weeks as the body adjusts

Obesity is big business with lots of money to be made