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Note This is an online update of the original version of this article that was published in the September 2025 issue of Medicine Today

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Using the standard pinch-and-90-degree-angle technique on your thigh ensures the needle reaches the appropriate depth in virtually all patients, regardless of body composition

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Similar results were observed in SURMOUNT4: the mean BMI by category at baseline was 29.1, 32.8, 37.4, and 45.3 kg/m 2 in the overweight, class I, II, and III obesity categories, respectively, and decreased to 24.4, 24.8, 27.7, and 32.4 kg/m 2 , respectively, by week 88 (Figure S1 in Supplementary Appendix)

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Testing ensures you and your provider optimize dosing around fresh, full-strength medication

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Two separate cohorts of rats were used in these studies

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