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Retatrutide's main side effects in trials: nausea (43%), heart rate increase of ~6.7 bpm, and dysesthesia (20.9%) at the 12 mg dose

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The glucagon-like peptide-1 receptor (GLP-1R) is a class B G proteincoupled receptor that regulates glucose homeostasis by promoting cAMP production and insulin secretion in pancreatic -cells

However, exercise shouldnt be done close to bedtime
